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1

Telomeres Acquire Embryonic Stem Cell Characteristics in Induced Pluripotent Stem Cells

Rosa M. Marion, Katerina Strati, Han Li, Agueda Tejera, Stefan Schoeftner, Sagrario Ortega, Manuel Serrano, Maria A. Blasco

Journal:

Year:

2009

Language:

english

File:

PDF, 2.05 MB

english, 2009

2

Different telomere-length dynamics at the inner cell mass versus established embryonic stem (ES) cells

Elisa Varela, Ralph P. Schneider, Sagrario Ortega and Maria A. Blasco

Journal:

Proceedings of the National Academy of Sciences

Year:

2011

Language:

english

File:

PDF, 2.01 MB

english, 2011

3

Nurses’ Emotions On Care Relationship: A Qualitative Study

Font‐Jimenez, Isabel, Ortega‐Sanz, Laura, Acebedo‐Uridales, Maria Sagrario, Aguaron‐Garcia, Maria Jesus, deMolina‐Fernández, Inmaculada, Jiménez‐Herrera, Maria F

Journal:

Journal of Nursing Management

Year:

2019

File:

PDF, 10.86 MB

2019

4

Cyclin D-dependent kinases, INK4 inhibitors and cancer

Sagrario Ortega, Marcos Malumbres, Mariano Barbacid

Journal:

Biochimica et Biophysica Acta (BBA) - Reviews on Cancer

Year:

2002

Language:

english

File:

PDF, 437 KB

english, 2002

5

Targeted Disruption of the FGF2 Gene Does Not Prevent Choroidal Neovascularization in a Murine Model

Takao Tobe, Sagrario Ortega, Jose D. Luna, Hiroaki Ozaki, Naoyuki Okamoto, Nancy L. Derevjanik, Stanley A. Vinores, Claudio Basilico, Peter A. Campochiaro

Journal:

The American Journal of Pathology

Year:

1998

Language:

english

File:

PDF, 1.05 MB

english, 1998

6

TRF1 is a stem cell marker and is essential for the generation of induced pluripotent stem cells

Schneider, Ralph P., Garrobo, Ianire, Foronda, Miguel, Palacios, Jose A., Marión, Rosa M., Flores, Ignacio, Ortega, Sagrario, Blasco, Maria A.

Journal:

Nature Communications

Year:

2013

Language:

english

File:

PDF, 3.20 MB

english, 2013

7

Constitutive activation of B-Raf in the mouse germ line provides a model for human cardio-facio-cutaneous syndrome

Jelena Urosevic, Vincent Sauzeau, María L. Soto-Montenegro, Santiago Reig, Manuel Desco, Emma M. Burkitt Wright, Marta Cañamero, Francisca Mulero, Sagrario Ortega, Xosé R. Bustelo, Mariano Barbacid an

Journal:

Proceedings of the National Academy of Sciences

Year:

2011

Language:

english

File:

PDF, 1.66 MB

english, 2011

8

A knockin mouse model for human ATP4a R703C mutation identified in familial gastric neuroendocrine tumors recapitulates the premalignant condition of the human disease and suggests new therapeutic strategies

Calvete, Oriol, Varro, Andrea, Pritchard, D. Mark, Barroso, Alicia, Oteo, Marta, Morcillo, Miguel Ángel, Vargiu, Pierfrancesco, Dodd, Steven, Garcia, Miriam, Reyes, José, Ortega, Sagrario, Benitez, Ja

Journal:

Disease Models & Mechanisms

Year:

2016

Language:

english

File:

PDF, 1.52 MB

english, 2016

9

A Cre-reporter transgenic mouse expressing the far-red fluorescent protein Katushka

Rodrigo Diéguez-Hurtado, Javier Martín, Inés Martínez-Corral, María Dolores Martínez, Diego Megías, David Olmeda, Sagrario Ortega

Journal:

Year:

2011

Language:

english

File:

PDF, 2.77 MB

english, 2011

10

Cdk2 is dispensable for cell cycle inhibition and tumor suppression mediated by p27Kip1 and p21Cip1

Alberto Martín, Junko Odajima, Sarah L. Hunt, Pierre Dubus, Sagrario Ortega, Marcos Malumbres, Mariano Barbacid

Journal:

Year:

2005

Language:

english

File:

PDF, 557 KB

english, 2005

11

Adult Sox2+ stem cell exhaustion in mice results in cellular senescence and premature aging

Vilas, Jéssica M., Carneiro, Carmen, Da Silva-Álvarez, Sabela, Ferreirós, Alba, González, Patricia, Gómez, María, Ortega, Sagrario, Serrano, Manuel, García-Caballero, Tomás, González-Barcia, Miguel, V

Journal:

Year:

2018

Language:

english

File:

PDF, 534 KB

english, 2018

12

A p53-mediated DNA damage response limits reprogramming to ensure iPS cell genomic integrity

Marión, Rosa M., Strati, Katerina, Li, Han, Murga, Matilde, Blanco, Raquel, Ortega, Sagrario, Fernandez-Capetillo, Oscar, Serrano, Manuel, Blasco, Maria A.

Journal:

Year:

2009

Language:

english

File:

PDF, 779 KB

english, 2009

13

M1756 Novel Immunologic Finding As One of the Probable Causes of Spontaneous Bacterial Peritonitis in Patients with Cirrhosis

Contreras-Contreras, Sagrario D., Guillen-Vargas, Cecilia M., Moreno-Luna, Laura E., Segura-Ortega, Jorge E., Fafutis-Morris, Mary

Journal:

Gastroenterology

Year:

2008

Language:

english

File:

PDF, 67 KB

english, 2008

14

The involvement of host replication proteins and of specific origin sequences in the in vitro replication of miniplasmid Rl DNA

Ortega, Sagrario, Lanka, Erich, Diaz, Ramon

Journal:

Nucleic Acids Research

Year:

1986

Language:

english

File:

PDF, 1.12 MB

english, 1986

15

Lymph Node Transplantation Results in Spontaneous Lymphatic Reconnection and Restoration of Lymphatic Flow

Aschen, Seth Z., Farias-Eisner, Gina, Cuzzone, Daniel A., Albano, Nicholas J., Ghanta, Swapna, Weitman, Evan S., Ortega, Sagrario, Mehrara, Babak J.

Journal:

Plastic & Reconstructive Surgery

Year:

2014

Language:

english

File:

PDF, 1.32 MB

english, 2014

16

Tumor lymphatic function regulates tumor inflammatory and immunosuppressive microenvironments

Kataru, Raghu P, Ly, Catherine L, Shin, Jinyeon, Park, Hyeung Ju, Baik, Jung Eun, Rehal, Sonia, Ortega, Sagrario, Lyden, David, Mehrara, Babak J

Journal:

Cancer Immunology Research

Year:

2019

File:

PDF, 3.87 MB

2019

17

A short G1 phase imposes constitutive replication stress and fork remodelling in mouse embryonic stem cells

Ahuja, Akshay K., Jodkowska, Karolina, Teloni, Federico, Bizard, Anna H., Zellweger, Ralph, Herrador, Raquel, Ortega, Sagrario, Hickson, Ian D., Altmeyer, Matthias, Mendez, Juan, Lopes, Massimo

Journal:

Nature Communications

Year:

2016

Language:

english

File:

PDF, 3.54 MB

english, 2016

18

Initiation of plasmid R1 replication in vitro is independent of transcription by host RNA polymerase

Diaz, Ramon, Ortega, Sagrario

Journal:

Nucleic Acids Research

Year:

1984

Language:

english

File:

PDF, 3.18 MB

english, 1984

19

Erratum to:Vegfr3-CreERT2mouse, a new genetic tool for targeting the lymphatic system

Martinez-Corral, Ines, Stanczuk, Lukas, Frye, Maike, Ulvmar, Maria Helena, Diéguez-Hurtado, Rodrigo, Olmeda, David, Makinen, Taija, Ortega, Sagrario

Journal:

Year:

2016

Language:

english

File:

PDF, 308 KB

english, 2016

20

The Ink4/Arf locus is a barrier for iPS cell reprogramming

Li, Han, Collado, Manuel, Villasante, Aranzazu, Strati, Katerina, Ortega, Sagrario, Cañamero, Marta, Blasco, Maria A., Serrano, Manuel

Journal:

Year:

2009

Language:

english

File:

PDF, 551 KB

english, 2009

21

Genetic rescue of Cdk4 null mice restores pancreatic β-cell proliferation but not homeostatic cell number

Martín, Javier, Hunt, Sarah L, Dubus, Pierre, Sotillo, Rocío, Néhmé-Pélluard, Fanny, Magnuson, Mark A, Parlow, Albert F, Malumbres, Marcos, Ortega, Sagrario, Barbacid, Mariano

Journal:

Year:

2003

Language:

english

File:

PDF, 336 KB

english, 2003

22

Single–Step Purification on DEAE–Sephacel of Recombinant Polypeptides Produced in Escherichia Coli

Ortega, Sagrario, García, José L., Zazo, Mercedes, Varela, Javier, Muñoz-Willery, Isabel, Cuevas, Pedro, Giménez-Gallego, Guillermo

Journal:

Year:

1992

File:

PDF, 454 KB

1992

23

Lockdown, Emotional Intelligence, Academic Engagement and Burnout in Pharmacy Students during the Quarantine

Moreno-Fernandez, Jorge, Ochoa, Julio J., Lopez-Aliaga, Inmaculada, Alferez, Maria Jose M., Gomez-Guzman, Manuel, Lopez-Ortega, Sagrario, Diaz-Castro, Javier

Journal:

Year:

2020

File:

PDF, 228 KB

2020

24

Isolation and characterization of a conditional replication mutant of the antibiotic resistance factor R1 affected in the gene of the replication protein RepA

Sagrario Ortega, Gertrudis Torrontegui, Ramón Díaz

Journal:

Molecular Genetics and Genomics

Year:

1989

Language:

english

File:

PDF, 809 KB

english, 1989

25

Deregulated expression of Cdc6 in the skin facilitates papilloma formation and affects the hair growth cycle

Búa, Sabela, Sotiropoulou, Peggy, Sgarlata, Cecilia, Borlado, Luis R, Eguren, Manuel, Domínguez, Orlando, Ortega, Sagrario, Malumbres, Marcos, Blanpain, Cedric, Méndez, Juan

Journal:

Year:

2015

Language:

english

File:

PDF, 1.82 MB

english, 2015

26

Evaluación global subjetiva y escala de malnutrición-inflamación para valorar el estado nutricional de pacientes en diálisis peritoneal con hipoalbuminemia

Jiménez Jiménez, Sagrario, Muelas Ortega, Francisca, Segura Torres, Pilar, José Borrego Utiel, Francisco, Gil Cunquero, José Manuel, Liébana Cañada, Antonio

Journal:

Enfermería Nefrológica

Year:

2012

File:

PDF, 471 KB

2012

27

Cyclin-dependent kinase 2 is essential for meiosis but not for mitotic cell division in mice

Ortega, Sagrario, Prieto, Ignacio, Odajima, Junko, Martín, Alberto, Dubus, Pierre, Sotillo, Rocio, Barbero, Jose Luis, Malumbres, Marcos, Barbacid, Mariano

Journal:

Nature Genetics

Year:

2003

Language:

english

File:

PDF, 3.00 MB

english, 2003

28

Genetic Analysis of Mammalian Cyclin-Dependent Kinases and Their Inhibitors

Malumbres, Marcos, Ortega, Sagrario, Barbacid, Mariano

Journal:

Biological Chemistry

Year:

2000

Language:

english

File:

PDF, 140 KB

english, 2000

29

Adult Sox2+ stem cell exhaustion in mice results in cellular senescence and premature aging

Vilas, Jéssica M., Carneiro, Carmen, Da Silva-Álvarez, Sabela, Ferreirós, Alba, González, Patricia, Gómez, María, Ortega, Sagrario, Serrano, Manuel, García-Caballero, Tomás, González-Barcia, Miguel, V

Journal:

Year:

2018

File:

PDF, 534 KB

2018

30

Overproduction and purification of biologically active native fungal α-sarcin in Escherichia coli

Lacadena, Javier, del Pozo, Alvaro Martínez, Barbero, JoséL., Mancheño, JoséM., Gasset, María, Oñaderra, Mercedes, López-Otin, Carlos, Ortega, Sagrario, Garcia, José, Gavilar, JoséG.

Journal:

Year:

1994

Language:

english

File:

PDF, 698 KB

english, 1994

31

In Vivo DNA Re-replication Elicits Lethal Tissue Dysplasias

Muñoz, Sergio, Búa, Sabela, Rodríguez-Acebes, Sara, Megías, Diego, Ortega, Sagrario, de Martino, Alba, Méndez, Juan

Journal:

Year:

2017

Language:

english

File:

PDF, 5.28 MB

english, 2017

32

A Second Heart Field-Derived Vasculogenic Niche Contributes to Cardiac Lymphatics

Lioux, Ghislaine, Liu, Xiaolei, Temiño, Susana, Oxendine, Michael, Ayala, Estefanía, Ortega, Sagrario, Kelly, Robert G., Oliver, Guillermo, Torres, Miguel

Journal:

Developmental Cell

Year:

2020

Language:

english

File:

PDF, 8.43 MB

english, 2020

33

cKit Lineage Hemogenic Endothelium-Derived Cells Contribute to Mesenteric Lymphatic Vessels

Stanczuk, Lukas, Martinez-Corral, Ines, Ulvmar, Maria H., Zhang, Yang, Laviña, Bàrbara, Fruttiger, Marcus, Adams, Ralf H., Saur, Dieter, Betsholtz, Christer, Ortega, Sagrario, Alitalo, Kari, Graupera,

Journal:

Year:

2015

Language:

english

File:

PDF, 6.50 MB

english, 2015

34

DnaA dependent replication of plasmid R1 occurs in the presence of point mutations that disrupt the dnaA box of oriR

Ortega-Jiménez, Sagrario, Giraldo-Suárez, Rafael, Fernández-Tresguerres, Maria Elena, Berzal-Herranz, Alfredo, Díaz-Orejas, Ramón

Journal:

Nucleic Acids Research

Year:

1992

Language:

english

File:

PDF, 1.73 MB

english, 1992

35

Generation of mice with longer and better preserved telomeres in the absence of genetic manipulations

Varela, Elisa, Muñoz-Lorente, Miguel A., Tejera, Agueda M., Ortega, Sagrario, Blasco, Maria A.

Journal:

Nature Communications

Year:

2016

Language:

english

File:

PDF, 2.43 MB

english, 2016

36

Hypoxia Induces Pluripotency in Primordial Germ Cells by HIF1α Stabilization and Oct4 Deregulation

López-Iglesias, Pilar, Alcaina, Yago, Tapia, Natalia, Sabour, Davood, Arauzo-Bravo, Marcos J., Sainz de la Maza, Diego, Berra, Edurne, O'Mara, Analia Nunez, Nistal, Manuel, Ortega, Sagrario, Donovan,

Journal:

Antioxidants & Redox Signaling

Year:

2015

Language:

english

File:

PDF, 952 KB

english, 2015

37

Vegfr3-CreERT2mouse, a new genetic tool for targeting the lymphatic system

Martinez-Corral, Ines, Stanczuk, Lukas, Frye, Maike, Ulvmar, Maria Helena, Diegez-Hurtado, Rodrigo, Olmeda, David, Makinen, Taija, Ortega, Sagrario

Journal:

Year:

2016

Language:

english

File:

PDF, 16.00 MB

english, 2016

38

A Genome-wide CRISPR Screen Identifies CDC25A as a Determinant of Sensitivity to ATR Inhibitors

Ruiz, Sergio, Mayor-Ruiz, Cristina, Lafarga, Vanesa, Murga, Matilde, Vega-Sendino, Maria, Ortega, Sagrario, Fernandez-Capetillo, Oscar

Journal:

Year:

2016

Language:

english

File:

PDF, 2.09 MB

english, 2016

39

Functional Reprogramming of Polyploidization in Megakaryocytes

Trakala, Marianna, Rodríguez-Acebes, Sara, Maroto, María, Symonds, Catherine E., Santamaría, David, Ortega, Sagrario, Barbacid, Mariano, Méndez, Juan, Malumbres, Marcos

Journal:

Developmental Cell

Year:

2015

Language:

english

File:

PDF, 5.84 MB

english, 2015

40

A p53-dependent response limits the viability of mammalian haploid cells

Olbrich, Teresa, Mayor-Ruiz, Cristina, Vega-Sendino, Maria, Gomez, Carmen, Ortega, Sagrario, Ruiz, Sergio, Fernandez-Capetillo, Oscar

Journal:

Proceedings of the National Academy of Sciences

Year:

2017

Language:

english

File:

PDF, 1.28 MB

english, 2017

41

Intranasal bevacizumab treatment on epistaxis in hereditary haemorrhagic telangiectasia: a case report

García-Martín, Estela, Pernía-López, Sagrario, Martínez-Ortega, Pilar A, Monje, Beatriz, Ruiz-Martínez, Cristina, Sanjurjo-Saez, María

Journal:

European Journal of Hospital Pharmacy Science and Practice

Year:

2017

Language:

english

File:

PDF, 277 KB

english, 2017

42

Synthesis and evaluation of arylquinones as BACE1 inhibitors, β-amyloid peptide aggregation inhibitors, and destabilizers of preformed β-amyloid fibrils

Andrea Ortega, Ángela Rincón, Karim L. Jiménez-Aliaga, Paloma Bermejo-Bescós, Sagrario Martín-Aragón, María Teresa Molina, Aurelio G. Csákÿ

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2011

Language:

english

File:

PDF, 274 KB

english, 2011

43

SIRT1 Is Necessary for Proficient Telomere Elongation and Genomic Stability of Induced Pluripotent Stem Cells

De Bonis, Maria Luigia, Ortega, Sagrario, Blasco, Maria A.

Journal:

Stem Cell Reports

Year:

2014

Language:

english

File:

PDF, 4.86 MB

english, 2014

44

ChemInform Abstract: Synthesis and Evaluation of Arylquinones as BACE1 Inhibitors, β-Amyloid Peptide Aggregation Inhibitors, and Destabilizers of Preformed β-Amyloid Fibrils.

Andrea Ortega, Angela Rincon, Karim L. Jimenez-Aliaga, Paloma Bermejo-Bescos, Sagrario Martin-Aragon, Maria Teresa Molina, Aurelio G. Csaky

Journal:

Year:

2011

Language:

english

File:

PDF, 32 KB

english, 2011

45

PdII-Catalyzed Conjugate Addition of Boronic Acids to Ketoglutaconic Esters toward the Synthesis of Functionalized Pyridazin-3(2H)-ones with Neuroprotective Activity

Silvia Roscales, Andrea Ortega, Sagrario Martín-Aragón, Paloma Bermejo-Bescós, Aurelio G. Csákÿ

Journal:

European Journal of Organic Chemistry

Year:

2012

Language:

english

File:

PDF, 493 KB

english, 2012

46

Basic Fibroblast Growth Factor Is Neither Necessary nor Sufficient for the Development of Retinal Neovascularization

Hiroaki Ozaki, Naoyuki Okamoto, Sagrario Ortega, Michelle Chang, Keiko Ozaki, Srinivas Sadda, Melissa A. Vinores, Nancy Derevjanik, Donald J. Zack, Claudio Basilico, Peter A. Campochiaro

Journal:

The American Journal of Pathology

Year:

1998

Language:

english

File:

PDF, 1.67 MB

english, 1998

47

Structural Modifications of Acidic Fibroblast Growth Factor Alter Activity, Stability, and Heparin Dependence

KENNETH A. THOMAS, SAGRARIO ORTEGA, DENIS SODERMAN, MARIE-THERESE SCHAEFFER, JERRY DISALVO, GUILLERMO GIMENEZ-GALLEGO, DAVID LINEMEYER, LINDA KELLY AND, JOHN MENKE

Journal:

Annals of the New York Academy of Sciences

Year:

1991

Language:

english

File:

PDF, 392 KB

english, 1991

48

Books received

De Bonis, Maria Luigia, Ortega, Sagrario, Blasco, Maria A.

Journal:

Cell Biology International Reports

Year:

1979

Language:

english

File:

PDF, 71 KB

english, 1979

49

The Meiotic Nuclear Lamina Regulates Chromosome Dynamics and Promotes Efficient Homologous Recombination in the Mouse

Link, Jana, Jahn, Daniel, Schmitt, Johannes, Göb, Eva, Baar, Johannes, Ortega, Sagrario, Benavente, Ricardo, Alsheimer, Manfred, Colaiácovo, Mónica P.

Journal:

Year:

2013

Language:

english

File:

PDF, 4.26 MB

english, 2013

50

ChemInform Abstract: Pd II -Catalyzed Conjugate Addition of Boronic Acids to Ketoglutaconic Esters Toward the Synthesis of Functionalized Pyridazin-3(2H)-ones with Neuroprotective Activity.

Roscales, Silvia, Ortega, Andrea, Martin-Aragon, Sagrario, Bermejo-Bescos, Paloma, Csaky, Aurelio G.

Journal:

Year:

2013

File:

PDF, 28 KB

2013

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